Lake Superior State University
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Tyler graduated from Saline High School in Saline, Michigan. He has been an active leader at Anchorhouse Christian Fellowship. He completed his senior research on the use of microreactors to produce pharmaceutical precursors. He was the recipient of a GRO Fellowship for Undergraduates sponsored by the EPA. Tyler completed a summer working in Cinncinati for the EPA's National Risk Management Research Laboratory, and spent a summer in San Francisco with the American Chemical Society's Nuclear Summer School. Tyler will be pursuing his PhD at Washington State University in the Fall.

Tyler O'Dell
2010 Outstanding Graduate
Chemistry

Department of Environmental Sciences

Degree Audits

The following Degree Audits are for our environmental programs effective Spring 2014.

NOTE: Historical degree audits

 

Synthesis of Multicyclic Products ...

Josh Brown

“Synthesis of Multicyclic Products from Annulation Reaction of an Imadazoline and β-Hydroxy Carboxylic Acids”: Imidazolines are nitrogen containing hetercycles that can be found in natural products. They have unique properties particularly their ability to react with electrophiles and nucleophiles. If reacted with a molecule that contains both, imidazolines can undergo annulations to produce many interesting products. This study attempted to prepare a multicyclic product from the reaction of 1-benzyl-2-phenyl-2-imidazoline with salicyloyl chloride or salicylic acid under three different conditions to determine which was optimal. The first reaction is a two step process that uses salicyloyl chloride produced from salicylic acid. The salicyloyl chloride is then used in an annulations reaction with the imidazoline. Production of salicyloyl chloride by known methods failed. Conditions two and three attempted a similar annulations using the coupleing reagents BOP-Cl and EDC with salicylic acid and the imidazoline. These reagents work to bond the carboxylic acid to the imidazoline N and make the reaction one step. The EDC reaction failed to produce the right product, the BOP-Cl reaction appeared successful based on GCMS. However, during the purification the product was not able to be isolated.

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