Alternatives to the Use of Animals in Research

Critics of animal research have suggested that most, if not all, uses of animals in research and education could be eliminated by the use of alternatives, such as tissue culture or computer models.  In 1986, the U.S. Congress Office of Technology Assessment produced an extensive study of the use of animal models and options for alternatives to animal use in research, education and testing.  The general conclusion of the report was that the very nature of the research in many areas makes it highly unlikely that reasonable alternatives to animal use will be developed.  A working definition of alternative techniques is “those techniques which replace the actual use of animals, reduce the numbers used, and/or refine the techniques to minimize the potential for the animal to experience pain or distress.”

Congress has been urged to provide funds specifically to develop alternatives to animal use in research, testing and education. Legislation has included requirements that alternatives be considered (e.g., the Health Research Extension Act of 1985 and the amended Animal Welfare Act) and NIH has a funding program for the development of methods which replace, reduce, or refine animal use.

Replacement
Reduction
Refinement

 

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