BIOL332 Embryology
(2,2) 3 (Alternate Years)
A study of pattern formation
and morphogenic processes
in animals, with an emphasis
on vertebrates. The laboratory
portion of the course
emphasizes descriptive
ontogeny of representative
vertebrates. Prerequisites:
BIOL131 and BIOL132.
(BIOL243 is highly
recommended.)
I first taught embryology in 1992, and have been fascinated with
the 'elegant complexity' of developmental biology ever since. I
focus on developmental processes in lecture while using the
laboratory to survey embryological development of selected
vertebrates.
In response to scheduling overlaps with other microscope-intensive courses, I experimented in the
mid 90s with digitizing embryology photomicrographs and teaching the lab using computers rather
than microscopes. However, imaging systems and storage capacity were limiting factors, and I
ultimately resumed using microscopes.
By 2005, advances in technology prompted an updated version of the digital approach to the lab.
I thus began development of the Digital Atlas of Vertebrate Embryology (DAVE). While my earlier
endeaver consisted of approximately 120 representative images from various serial sections,
DAVE includes over 5500 images, comprising complete serial sections of each embryo at multiple
developmental stages. Each image is digitally enhanced and incorporated into an interactive
Flash© movie. These movies enable one to quickly locate a specific region of the embryo and
then step through section by section. DAVE also
makes it easy to switch between whole mounts,
sagittal, transverse, and frontal sections.
The difference between DAVE and the earlier
version goes beyond mere numbers of images. By including every image in each serial section
and providing tools to move rapidly between images, students acquire a better understanding of
the 3-dimensional nature of the embryo – typically the most difficult aspect of this lab.
updated 11/18/2010