Lake Superior State University
Lake Superior State University
 
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Alum Success

23 Michigan Conservation Officers - all LSSU alumni - met up at Camp Grayling

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Criminal Justice
Outstanding reputation for producing well educated and well trained criminal justice practitioners
Facilities
   

Crime Lab
Students learn proper forensic techniques within one of our dedicated criminalistics labs.


LSSU is one of a few criminal justice programs to offer students an on site shooting range.

  

 

Towards the Synthesis of a Guanidine- like Organo- catalyst

Rebecca Smrke

In the last decade, N-based heterocycles have surfaced as useful organocatalysts. With strong Lewis basicity, a rigid structure that allows for strong resonance, and electronic distribution, these catalysts become useful in both medicinal and industrial chemistry purposes. The desire to created new and unique cyclic guanidine catalysts has generated interest in this field. We proposed to synthesize cyclic guanidine catalysts through a short three step process: (1) alkylation of a commercial imidazoline, (2) annulations with the use of a β-aminocarboxylic acid under dehydrating conditions, and (3) thermal elimination. The first step, alkylation, was successfully completed. In step 2, the annulations reaction, there is evidence that it may have proceeded, but more research is needed to verify the result. As such, the final step of forming an organocatalyst, elimination, could not be completed. In the future, the reaction will be optimized to yield the desired product.

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